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Low Grade Chronic Inflammatory Response in Pathogenicity of Diabetes Mellitus

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    CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS Authored by Shamim Shaikh Mohiuddin  Abstract Acute phase reaction which is mainly cytokine-mediated is observed to be closely involved in the pathogenesis of type 2 diabetes. Since maximum world populations are at elevated risk of developing diabetes, we tested this hypothesis by estimating circulating acute phase proteins in type 1(T-1), type 2 (T-2) diabetic patients and type 2 diabetic patients under oral hypoglycemic drugs for duration of at least 5 years. The acute phase proteins, α1- antitrypsin, α1- acid glycoprotein, ceruloplasmin and fibrinogen were estimated in the plasma in newly diagnosed 12 T-1 cases, newly diagnosed 25 T-2 cases and 25 T-2cases under oral hypoglycemic agent for at least 5 years Thirty normal controls to match the age and sex of the test groups were also studied. The levels of these proteins were correlated with their BMI and random plasma glucose values. In com...

Effect of Vitamin D on Glucose Homeostasis, Sensitivity and Insulin Resistance in Type 2 Diabetes

  Abstract Background: In recent years, non-bone diseases have been reported with vitamin D deficiency, one of them is type 2 diabetes, which is a group of metabolic disorders caused by insulin action deficiency. Evidences suggest that vitamin D deficiency affects the metabolic function of cells, including beta-pancreatic cells. Regarding the fact that some studies have shown the effect of vitamin D on control of type 2 diabetes, the present study aims to review on the relationship between vitamin D, glucose homeostasis and insulin resistance type 2 diabetes. Methods: This study is a review on descriptive and analytic studies which accessed data using biochemical tests, questionnaires and interviews. By using key words on vitamin D, type 2 diabetes and insulin resistance, 10 articles including descriptive-analytic, cross-sectional, case-control and interventional types from 1986 to 2018 were conducted. Results: Many studies have shown that vitamin D leve...

Type 1 Diabetes: Causes, Symptoms and Treatments, Review with Personal Experience

  Abstract Type 1 diabetes is an auto-immune disorder commonly occurring in the young. The exact cause of this type of diabetes is not yet known and most people suffering from this chronic illness do not know how to manage and avoid diabetic complications. Parents lack knowledge to help their child manage Type 1 diabetes leading to depression. The author herself is diagnosed with Type 1 diabetes and most explanations reported in this paper are from her personal experience and research. She hopes it will provide a better understanding and control of this disorder for those suffering from it.  Read More About This Article: https://juniperpublishers.com/crdoj/CRDOJ.MS.ID.555817.php Read More Juniper Publishers Google Scholar Articles:  https://scholar.google.com/citations?view_op=view_citation&hl=en&user=KKJjfyEAAAAJ&citation_for_view=KKJjfyEAAAAJ:DIubQTN3OvUC    

Importance of Screening for Wellbeing in Diabetes Management

  Abstract Diabetes (Type 1 and 2) is a chronic metabolic disorder impacting both the mind and the body of the individual. The impact on the mind includes emotional, social, cognitive and psychosocial wellbeing of the individual. Thus, diabetes management must not only focus on the impact of the disease on the body but also understand its cognitive, psychological and lifestyle implications. Given the negative impact of the stress on both the mind and the body, stress screening and management must be incorporated in diabetes management. This review explores stress, its impact on physical and psychological wellbeing in the context of diabetes management. Evidence is presented on the challenges related to measurement of stress and its negative impact on the wellbeing of the individual. Based on the comparison (complexity, scalability, etc.) between measurement of stress and wellbeing, the review highlights the importance of screening for wellbeing using simple psych...