Juniper Publishers-Journal of Diabetes Obesity Journal

CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS Authored by Murillo Ortiz Blanca Abstract Telomeres are structures at the ends of eukaryotic chromosomes and consist of tandemly repeated DNA sequences. Telomeres shorten with each cell division, and it is well known that telomere length in peripheral blood mononuclear cells (PBMCs) decreases with age. High oxidative stress can lead to accelerated telomere shortening, which causes premature cell senescence. In summary, this review shows the short Telomere Length has been identified in a limited number of population studies as a risk factor for development of T2DM. Also, it is importantly to notice the antioxidant properties of Curcumin which may play a key role in the prevention and treatment of premature aging while preserving the length of the telomeres. Keywords: Telomere shortening; Oxidative stress; Genetic factor; Diabetes mellitus 2 Abbreviations: T2DM: Diabetes Mellitus...

CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS Authored by Mariusz Jaworski Introduction In the World a significant percentage of people are characterized by unhealthy lifestyle, especially bad food habits, and physical inactivity. This unhealthy lifestyle could be a cause of many lifestyle diseases or diseases of civilization. If epidemiological date is anything to go by the most common lifestyle diseases are obesity, and diabetes [ 1 , 2 ]. Epidemiological data suggest that about 8.5% of adults aged 18 and older had diabetes in 2014. In the same year, high blood glucose was the cause of another 2.2 million deaths. Moreover, it is reported that overweight and obesity account for an estimated 8%-15% of the burden of disease in industrialized countries. What is more, World Health Organization (WHO) estimated that more than 1.9 billion adults aged 18 and older were overweight in 2014. In the same year, about 13% of the world'...