Juniper Publishers-Journal of Diabetes Obesity Journal

      CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS   Authored by Amelia Oleaga Abstract Dulaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1RA) used in the treatment of Type 2 Diabetes Mellitus which has been shown to be effective in reducing HbA1c and weight with a high degree of safety. Aims:  To evaluate the effectiveness of 1.5mg weekly dulaglutide under condition of routine clinical practice. The safety and discontinuation rate and its cause were quantified. The results obtained were compared with those published in randomised clinical trials and other observational studies. Subjects and Methods: 208 patients were included in this study, mean age was 62 years, BMI 35.7kg/m2 and HbA1c was 8.48%. Results:  The results showed a statistically significant reduction in HbA1c of -0.95% and in mean weight of -4.63Kg after 24 months follow-up. The drug’s effect was lower in patients who had received previous treatment with another GLP-1RA, and in pati

                                  CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS Authored by Yo Tsuchiya Abstract Dietary fiber (indigestible polysaccharides) intake is widely recommended as a nutritional therapy to improve hyperglycemia and diabetes. Many researchers have reported the beneficial effects of dietary fibers such as cellulose, pectin, inulin, and guar as regulators of glucose metabolism. In addition, new types of indigestible polysaccharides have been shown to be novel dietary fibers that attenuate postprandial glycemia. This review summarizes the understanding and progress of traditional and recent studies on the effects of dietary fiber on glucose metabolism. Keywords:  Dietary fiber; Glycemia; Diabetes; Glucose absorption; Intestinal microbiota; Proteoglycan Abbreviations:  SCFA: Short-chain fatty acids; PG: Proteoglycans; IMD: Isomaltodextrin Go to Introduction Various medical and nutritional therapies have been developed worldwide to improve

      CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS Authored by Mohammad Soltanizadeh Abstract This study aimed to evaluate the effectiveness of mindfulness-based cognitive therapy on sexual self-esteem in obese women. The design of the present study was a quasi-experimental design with pre-test, post-test, and 6-months follow-up and control group. Using the convenience sampling method, 30 obese women were selected and randomly assigned to experimental and control groups. The experimental group received 8 sessions of mindfulness-based cognitive therapy intervention. The female sexual self-esteem scale in the pre-test, post-test, and follow-up stages was performed for both groups and the findings were analyzed using two-way repeated measures ANOVA. The results showed that there was a significant difference between the experimental and control groups in the component of sexual self-esteem in the post-test and follow-up stages (P<0.05). Based on these findings

    CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS Authored by MSI Tipu Chowdhury Abstract Background:  As a well-established risk factor for coronary heart disease, Metabolic Syndrome was already encountered. But the relationship between Metabolic Syndrome and Type 2 Diabetes Mellitus and independent contribution of Metabolic Syndrome remained unclear. To evaluate the status of metabolic syndrome in Type 2 diabetic population and for their ability to predict Type 2 Diabetes Mellitus, in parallel with conventional stroke risk factors, this study was planned. Methods:  A hospital based descriptive observational study was conducted in 100 patients with Type 2 Diabetes Mellitus who were selected by consecutive random sampling technique. Patients were diagnosed through proper history, clinical examination and necessary investigations. The outcome values were measured in the form of anthropometric measurements, blood pressure, dyslipidemia and blood glucose. Results