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Waist to Height Ratio is the Preferred Way to Measure the Association between Obesity and Bisphenol a Exposure

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    CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS   Authored by Nathaniel R Geyer   Abstract Bisphenol A-induced weight gain using four body measurements (body mass index, waist circumference, waist to height ratio & adult body fat percentage), in adults 18-74 years has been connected with obesity and diabetes. So a cross-sectional analysis of urinary bisphenol A concentrations by four body measurements, using six pooled datasets from the 2003-2014 biennial National Health and Nutritional Examination Surveys. After adjustment by survey year, age, race, gender, diabetic status, education level, and smoking status, obesity was positively associated odds ratios of having bisphenol A exposure in each of the four body measurements. In addition, bisphenol A exposures of 1.73-3.52ng/mL had highest chances of being either obese or overweight. Higher bisphenol A exposure had association with obesity when using the waist to height ratio cutoff (≥0.58) a

Analysis of Inflammatory Cytokines in Pre-Diabetic Subjects

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  CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS       Authored by Saket Gupta   Abstract Objective: Pre-diabetes is defined as either impaired fasting glucose ((IFG) between 5.6 and 6.9mmol/l) or impaired glucose tolerance (IGT) wherein fasting or post-prandial plasma glucose levels are above normal levels, but below that of clinical Type-2-Diabetes Mellitus (T2DM). Both IFG and IGT, risk factors for T2DM and macrovascular diseases, have previously been linked with inflammation. With this in mind, we sought to comparatively evaluate the levels of inflammatory markers in pre-diabetics relative to normal healthy individuals. Methods: We determined the levels of serum cytokines in a cohort of 9 patients with pre-diabetes and thirty four individuals with normal glucose control using a 96-Well Multi-array 7-plex assay or 1-plex IFN-β and Rantes 96-well plates (Meso Scale Discovery, Gaithersburg, Maryland, USA). Results: Our study demonstrated