Clock Genes, Chronodisruption, Nutrition and Obesity_Juniper Publishers
CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS Authored by Francisco J Sánchez Muniz Abstract The existence of biological clocks has been demonstrated in all living beings. Such clocks control the physio-metabolic activities of cells, organs and systems to warrantee efficacy in the process to obtain energy and metabolize nutrients under a homeostatic point of view. These ordered activities are known as circadian rhythms, occurring approximately every 24h, and depend on the activity of groups of neurons (oscillators) negatively interrelated. The oscillatory activity is related to gene expressions that implicate rhythms in the mRNA and protein production. However, alterations in such synchronism is frequently found because of many of human activities are performed in "unexpected” environmental conditions. Thus, light intensity and environmental temperature are normally rather constant; in addition light/darkness cycles are