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Hyperglycaemia, Pre-Diabetes and Diabesity: Can we Choose who to 'Fast-Track' into Diabetes Prevention?

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CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS Authored by Sally D Poppitt Abstract Global numbers of overweight and obesity have been increasing steadily for the past few decades, driving a rapid parallel increase in type 2 diabetes (T2D) morbidity and associated mortality. Hindered by our inability to clearly define the characteristics and therefore the assessment biomarkers for 'pre-diabetes', there remains significant difficulty in identifying those most at risk, essential in order to prioritize public health initiatives for those who would most benefit from 'fast-track' prevention. Implementation of a population-wide approach to T2D prevention is likely to be prohibitively expensive and unsuccessful, so more focused strategies are required. 'Pre-diabetes' is defined by any/all of 4 biomarker methods, comprising impaired fasting glucose (IFG), impaired glucose tolerance (IGT), IFG plus IGT, and mildly ra

Juniper Publishers: Rare Complications of Caudal Epidural Steroid Inje...

Juniper Publishers: Rare Complications of Caudal Epidural Steroid Inje... : Journal of Head Neck & Spine Surgery   Opinion The caudal epidural steroid injection reported in 1952 helps to treat low back ...

Immunology and Systemic Inflammation Biomarkers Among Saudi Patients with Sickle Cell Anemia in Asymptomatic Steady State Condition

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  CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS Authored by Fadwa M Alsharif Abstract Background & Objective: Sickle cell anemia (SCA) comprises an inherited blood disorder that is lifelong and affects many people globally. Despite progress in therapy, SCA is a considerable cause of mortality and morbidity. This study was designed to measure the immunological parameters and inflammatory cytokines of Saudi patients with sickle cell anemia (SCA) in asymptomatic steady state. Material and Methods: Fifty asymptomatic sickle cell anemia patients and fifty age- and sex-matched healthy non-sickle cell disease subjects were involved in this study. Results: The number of white blood cells, neutrophil, lymphocytes, eosinophils, basophils, CD3, CD4 and CD8 count were significantly elevated in stable-state SCA patients when compared with healthy controls. In addition, the mean value of CRP, TNF-α, IL-2, IL-4, IL-6 and IL-8 w