Juniper Publishers-Journal of Diabetes Obesity Journal

    CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS Authored by Zeinab Jannoo Introduction Health-Related Quality of Life (HRQoL) assesses the impact of illnesses on the physical, mental and social well-being of individuals and its importance is increasingly recognized [1]. Some instruments are intended for general use, irrespective of illness and the condition of the patient. The generic instruments may often be applicable to healthy people too. Some of the earliest ones were developed initially with population surveys in mind, but later was extended to include clinical trial settings. These instruments are commonly described as Quality of Life (QoL) scales and they are measures of health status since the focus is mainly on physical symptoms. Whilst the generic QoL instruments measure QoL generally and assess the various health domains, the diabetes-specific QoL is more sensitive to changes and is specific to the disease per se [2]. There are many instruments t

  CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS Authored by  Khaled K Al-Qattan Commentary To some diabetalogists/diabeticians, and certainly the majority of the general public, the title of this commentary might come a bit as a surprise. What is known about diabetes mellitus (DM), as a medical condition, that it is a group of linked biochemical-physiological disorders initiated by pathological rise in the circulating blood glucose concentration. This hyperglycemia develops mostly as a consequence to either hypoinsulinemia (DM type-1) or cellular insensitivity to insulin (DM type-2). In extreme cases both causative factors transpire and therefore act together on the body leading to the induction and progression of an aggressive form of the disease. For the time being, DM is unequivocally regarded as an inherent condition since its causes’ are innate to the affected person and provoked primarily by life-style and genetics. Although this self-origin manifestatio

                            CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS Authored by H Allgayer Abstract Patients with obesity and/or type 2 diabetes have an increased tumor risk including colorectal cancer. Physical acrtivity (PA), exercise (EX) and weight reduction (WR) are effective strategies to decrease this risk. Highly sensitive tumor risk biomarkers such as oxidative DNA damage products (8-oxo-2’deoxyguanosine [8-oxo-dG]) increasingly are used in epidemiological and clinical (intervention) studies to better quantify this risk and to investigate potential effects of PA/EX/WR on this biomarker with the aim to further improve prevention and patient management programs. Based on the available data a U-shaped relationship between urinary 8-oxo-dG excretion and the level of PA/EX intensity is assumed, on the other hand, the relationship with BMI seems to be less clear. In this minireview this data will be discussed with regard to clinical and epidemiologic

  CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS  Authored by Sinisa Franjic Abstract Diabetes in pregnancy can significantly endanger the health of a pregnant woman, especially the vulnerable population and her child, and it is extremely important to talk about this disease. Diabetes mellitus or diabetes is a metabolic disease in which there is a chronic condition of elevated blood sugar levels (hyperglycemia) due to insufficient action of insulin, a hormone secreted by the pancreas. In some cases of the disease, insulin is not produced or is produced very little, and in other cases it is produced even in increased amounts, but the cells are resistant to its action, which is called insulin resistance. Sugar, or glucose, is the fuel that the human body needs to function properly. It is a source of energy for all the cells in our body and is created by the breakdown of carbohydrates in the digestive system. In order for our cells to be able to use the obtained g

    CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL   JUNIPER PUBLISHERS   Authored by Gudisa Bereda Abstract Diabetic foot ulcer is one of the major health challenges that can decrease the quality of life, lengthen hospitalization and entails more cost to the patient. Diabetic foot disease outcome fifteen percent of the diabetic patients and person with diabetes are fifteen times more probably to undergo lower extremity amputation than their non-diabetic counterpart. Risk factors for ulceration are specific or systemic contributions such as uncontrolled hyperglycemia, duration of diabetes, peripheral vascular disease, blindness or visual loss, chronic renal disease, advanced age and local issues such as peripheral neuropathy, structural foot deformity, trauma and incorrectly suited shoes, callus, history of prior ulcer amputation, delayed elevated pressures, limited joint mobility. The initial goals of treatment for diabetic foot ulcer are to acquire wound closure as expeditiously