Juniper Publishers-Journal of Diabetes Obesity Journal

  CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS     Authored by Surapon Tangvarasittichai Abstract Cardiovascular disease (CVD) is common occur in type 2 diabetes mellitus (T2DM) patients. We aim to evaluate the association of cardio-ankle vascular index (CAVI) with the CVD risk factors. Anthropometric and CAVI measurements, blood pressure (BP) and biochemical variables were measured. One hundred and eighty seven women were allocated to 2 groups. Group (Gr)-1; 56T2DM patients with CAVI>0.9 were significantly higher in age, BP, mean arterial pressure (MAP), fasting blood sugar (Glu), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL-C), hs-CRP, insulin, insulin resistance (HOMA-IR) and significantly lower in BMI, high density lipoprotein (HDL-C)levels than Gr-2; 131 non-T2DM subjects with CAVI<0.9. In bivariate correlation, CAVI was significantly correlated with Age, BMI, MAP, TC, HDL-C and hs-CRP (p<0.05). Multip

CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS Authored by Kumaravel Velayutham Abstract The single chain proteo-hormone leptin is recognized to play a vital role in the regulation of fat metabolism and storage. Circulating leptin concentration is considered to be reflective of body mass and is primarily tied up with the proportion of adipose tissue. Emerging evidences have indicated that leptin levels are modulated in diabetic conditions and leptin therapy significantly improves diabetic disease management. The present review focuses to discuss the variations in the leptin levels, the potentiality of Leptin therapy in type I diabetes. Keywords:  Leptin levels; Adipose tissue; Obesity; Type I diabetes Go to Introduction Leptin is a single chain proteo-hormone product of the ‘ob‘gene and is recognized to play a vital role in the regulation of fat metabolism and storage. Predominantly made by the adipose cells, leptin primarily helps to regulate energy balance by