Juniper Publishers-Journal of Diabetes Obesity Journal

  CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS     Authored by Kanwaljit Chopra   Abstract Insulin resistance (IR) is an important link between obesity and post obesity complications varying from diabetes mellitus to neurological insults such as cognitive dysfunction and Alzheimer's disease. Currently available high calorific diet induced preclinical models mimic clinical pathologies of various metabolic disorders but they are highly time consuming. Zymosan a well-known inflammagen has recently been used to induce reversible IR conditions in rodent models. Though, the insulin resistance lasts as long as zymosan is injected to animals, but the pathogenesis that resembles to that of obesity, IR and metabolic syndrome. However, high fat or high carbohydrate diet could be used in combination with zymosan to develop a novel animal model of IR where both inducers act synergistically to exert their primary actions. The combination of these two

  CURRENT RESEARCH IN DIABETES & OBESITY JOURNAL JUNIPER PUBLISHERS       Authored by Kazue Sawami   Abstract Introduction: Alzheimer's type dementia (AD) accounts for at least 60% of total dementia cases. Furthermore, in people over the age of 65 the incidence rate doubles, which highlights the urgent need to develop preventative measures or delay disease onset. Therefore, we carried out a study involving interventions that combined group-games and brain training among the elderly in the Kashihara-City. Additionally, in order to determine the relation between body composition and cognitive function, we carried out the measurements with an inner scan monitor. Further, to quantify the relationship between stress and cognitive function, the degree of stress was measured using salivary gland amylase levels. The purpose of this study was to examine the effect of interventions in combinations of group-games and brain training on cognitive function, and determine the